Unisom (Doxylamine) 25mg Tablets


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Unisom (Doxylamine) 25mg Tablets

Unisom (Doxylamine) 25mg Tablets are used to treat difficulty falling asleep, commonly known as insomnia. These tablets contain a medication called doxylamine, which belongs to a class of drugs known as antihistamines.

Mechanism of Action

Doxylamine is a histamine antagonist that works by blocking the effects of histamine, a naturally occurring substance in the body that is involved in sleep regulation. By blocking histamine, doxylamine helps promote relaxation and sleep.

Dosage and Administration

The recommended dosage is 25mg orally, taken before bedtime. It is important to follow the dosage instructions provided by your healthcare provider. Swallow the tablets whole with a glass of water. Do not crush, chew, or dissolve the tablets.

Side Effects

Common side effects of Unisom (Doxylamine) 25mg Tablets include dry mouth, drowsiness, and dizziness. These side effects are usually mild and temporary. If they persist or become bothersome, contact your healthcare provider.


Before taking it, tell your healthcare provider about any other medications you are taking, including over-the-counter medications, vitamins, or herbal supplements. Some medications may interact with doxylamine and affect its efficacy or safety.


Unisom (Doxylamine) 25mg Tablets may not be suitable for everyone. Some contraindications include:

– Hypersensitivity to doxylamine or any components of the formulation.

– Severe liver disease.

– History of seizures or convulsions.

– Narrow-angle glaucoma.

– Obstructive sleep apnea.


Do not use it if you are pregnant, breastfeeding, or planning to become pregnant. The use of doxylamine during pregnancy or breastfeeding is not recommended.

Drug Interactions

Certain medications can interact with that and affect its efficacy or safety. Tell your healthcare provider about all the medications you are taking, including prescription and over-the-counter medications, vitamins, and herbal supplements.


If you suspect an overdose, contact your local poison control center or seek immediate medical attention.


Store it at room temperature, away from moisture and heat. Keep them out of reach of children and dispose of any unused or expired tablets properly.


Unisom (Doxylamine) 25mg Tablets are used to treat difficulty falling asleep. They work by blocking the effects of histamine and promoting relaxation and sleep. Follow your healthcare provider’s instructions, and contact your healthcare provider if you experience any side effects or if your condition worsens.

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